Market research
 

THET PAING SOE’S operating culture alongside talented, well-trained and experienced personnel, our sales team has steered its course through vast network of distribution pipelines throughout Myanmar.



On a regular basis, our professional sales representatives visit our customers to fulfill their needs not only by collecting orders but also by sharing useful and updated information as well.

Regulatory Affairs
• Regulatory Affairs services
• Updated laws and health regulations
• PV reports


We can handle and provide Regulatory Affairs services to our valued partners who are in need. In addition, updated laws and health regulations and Pharmacovigilance reports could also be provided by our Regulatory Affairs Department.

 

 
 
Marketing Management

THET PAING SOE has its core marketing team with enough knowledge & skills through which it can provide all clinicians with complete, accurate, comprehensive and impartial information regarding pharmaceuticals.

Market research
 


As part of the requirements of marketing management, we conduct market research in order to make sure understanding of the market situation and consumer’s behavior.
Nationwide Distribution
 


We have our own wholesales & retail sales outlets in Yangon & Mandalay. Through these outlets as well as our Van Sales, we offer a nationwide distribution designed to cover important parts of the country.

We provide the efficient delivery service within 24 hours after receiving an order and also serve an urgent delivery in order to fulfill customers’ special needs.

Logistics
  • Application for Import License
  • • Customs clearance
  • Payment remittance
All importation procedures: Application of IL at the Ministry of Commerce, Customs clearance on the product arrival and payment remittance to the related banks are performed by our Logistics Team.
 

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Essential Amino Acids for Renal Failure

ESSENTIAL AMINO ACID PREPARATION

Essential amino acid preparation for renal failure

DESCRIPTION AND COMPOSITION

AMIYU Granules is packaged granules containing 2.5 g per pack. The contents are white-coated granules with aromatic odour and slightly sweet taste. Composition AMIYU Granules contains the following ingredients in a pack (2.5 g).

Contains the following ingredients in a pack (2.5g)

Active Ingredients Content of EAA/ sachet     
L-isoleucine 203.9 mg
L-leucine 320.3 mg
L-lysine hydrochloride 291.0 mg
L-methionine 320.3 mg
L-phenylalanine 320.3 mg
L-threonine 145.7 mg
L-tryptophan 72.9 mg
L-valine 233.0 mg
L-histidine hydrochloride 216.2 mg
Essential Amino acids total          2123.6 mg


PHARMACOLOGICAL PROPERTIES Pharmacodynamics

1. Effects and actions Clinical experiments: In clinical tests on 20 patients with chronic renal failure, such effects were noted as improvements of nitrogen balance, decrease of serum urea nitrogen, increase of total serum protein, albumin and hemoglobin,inhibition of production of uremic toxins and the delay of the aggravation ofrenal failure state.

2. Mechanism of action The therapy with AMIYU Granules is based on when 8 kinds of essential amino acids and L-histidine which is necessary in patients with renal failure are administrated, non-essential amino acids are biosynthesized from urea nitrogen with sufficient energy, the subsequent protein is synthesized, and the accumulation of waste nitrogen metabolites is inhibited. It is confirmed the therapy with AMIYU Granules makes the improvement clinical symptom and the delay of disease aggravation.

INDICATIONS

Supply of amino acids in chronic renal failure

CONTRAINDICATIONS

Patients with severe hepatic function disorder [Imbalance of amino acids may be aggravated with the use of AMIYU Granules, resulting in the induction of hepatic coma.]

DOSAGE AND ADMINISTRATION Dosage

The usual adult dosage for oral use is each pack for one time and three times daily after meals. The dosage should be adjusted depending on the patient’s age, severity of symptoms, and body weight. Method of administration Oral use.

PRECAUTIONS

Read carefully the instructions before use. For further information please consult your doctor. This drug is used upon doctor's prescription only.
Important Precautions AMIYU Granules should be used for maintenance therapy for the patients with chronic renal failure. Use in the Elderly In general, since physiological function is decreased in the elderly, AMIYU Granules should be carefully administered, such as reducing the dose. Use during Pregnancy, Delivery or Lactation(1) AMIYU Granules should only be used in pregnant women or women who may possibly be pregnant only if the expected therapeutic benefits outweigh the possible risks associated with treatment. [The safety of this product during pregnancy has not been established.](2) Use of AMIYU Granules in nursing women is not recommended. If use of AMIYU Granules is judged to be essential, breast feeding must be discontinued during treatment. [The safety of this product in nursing women has not been established.] Pediatric Use The safety of AMIYU Granules in children has not been established. [There is insufficient clinical data.] Precautions concerning Use At the time of administration, patients must be provided with low-protein diet according to their renal function and their calorie intake should be 1,800 Kcal or more.

INTERACTION WITH OTHER DRUGS AND OTHER FORMS OF INTERACTIONS

There is no report to indicate the interaction with other drugs.

ADVERSE REACTIONS

Adverse reactions to AMIYU Granules was observed in 132 (2.37%) of total5564 cases. The most frequently observed adverse reactions were nausea/queasy in 70reactions (1.26%), anorexia in 41 reactions (0.74%), vomiting in 24 reactions(0.43%), abdominal bloating in 19 reactions (0.34%), oral discomfort (including mouth feeling dry, thirst) in 14 reactions (0.25%), and increased AST (GOT) and ALT (GPT) in 9 reactions (0.16%). (At the end of the re-examination)

SHELF-LIFE

36 months from manufacturing date.

STORAGE

Store below 30C.

PACKING SIZE

Box of 210 aluminum sachets x 2.5 g Box of 630 aluminum sachets x 2.5 g

Keep out of reach of children. Do not use the medicine after the expiry date stated on the package.